Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance

Environments surrounding G-rich sequences remarkably affect the conformations of these structures. A proper evaluation system mimicking the crowded environment in a cell with macromolecules should be developed to perform structural and functional studies on G-quadruplexes. In this study, the topolog...

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Bibliographic Details
Main Authors: Shi-Ke Wang, Hua-Fei Su, Yu-Chao Gu, Shu-Ling Lin, Jia-Heng Tan, Zhi-Shu Huang, Tian-Miao Ou
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580815001028