Vascular smooth muscle cells in response to cholesterol crystals modulates inflammatory cytokines release and promotes neutrophil extracellular trap formation

Vascular smooth muscle cells in response to cholesterol crystals modulates inflammatory cytokines release and promotes neutrophil extracellular trap formation

Abstract Background The formation and accumulation of cholesterol crystals (CC) at the lesion site is a hallmark of atherosclerosis. Although studies have shown the importance of vascular smooth muscle cells (VSMCs) in the disease atherosclerosis, little is known about the molecular mechanism behind...

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Bibliographic Details
Main Authors: Jishamol Thazhathveettil, Ashok Kumar Kumawat, Isak Demirel, Allan Sirsjö, Geena Varghese Paramel
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Molecular Medicine
Subjects:
Cholesterol crystal
Vascular smooth muscle cells
Atherosclerosis
Neutrophil extracellular traps
Inflammation
Cardiovascular disease
Online Access:https://doi.org/10.1186/s10020-024-00809-8

Internet

https://doi.org/10.1186/s10020-024-00809-8

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