Phosphatase-dependent regulation of epithelial mitogen-activated protein kinase responses to toxin-induced membrane pores.

Phosphatase-dependent regulation of epithelial mitogen-activated protein kinase responses to toxin-induced membrane pores.

Diverse bacterial species produce pore-forming toxins (PFT) that can puncture eukaryotic cell membranes. Host cells respond to sublytic concentrations of PFT through conserved intracellular signaling pathways, including activation of mitogen-activated protein kinases (MAPK), which are critical to ce...

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Bibliographic Details
Main Authors: Jorge L Aguilar, Ritwij Kulkarni, Tara M Randis, Sandeep Soman, Alexander Kikuchi, Yuxin Yin, Adam J Ratner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2778951?pdf=render

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http://europepmc.org/articles/PMC2778951?pdf=render

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