Monoclonal Antibodies Bind a SNP-Sensitive Epitope that is Present Uniquely in Mycobacterium avium subspecies paratuberculosis

Monoclonal Antibodies Bind a SNP-Sensitive Epitope that is Present Uniquely in Mycobacterium avium subspecies paratuberculosis

Due to a close genetic relatedness, there is no known antibody that detects M. avium subspecies paratuberculosis (MAP), which causes Johne’s disease in cattle and sheep, and does not cross-react with other M. avium subspecies. In the present study, a monoclonal antibody (17A12) was identified from...

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Bibliographic Details
Main Authors: John P Bannantine, Judy eStabel, Elise eLamont, Robert E Briggs, Srinand eSreevatsan
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Antibodies
Antigens
detection and diagnostics
Johne’s disease
Mycobacterium paratuberculosis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00163/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00163/full

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