ALDH1A3 Segregated Expression and Nucleus-Associated Proteasomal Degradation Are Common Traits of Glioblastoma Stem Cells

ALDH1A3 Segregated Expression and Nucleus-Associated Proteasomal Degradation Are Common Traits of Glioblastoma Stem Cells

Aldehyde dehydrogenase 1 isoforms A1 and A3 have been implicated as functional biomarkers associated with distinct molecular subtypes of glioblastoma and glioblastoma stem cells. However, the exact roles of these isoforms in different types of glioma cells remain unclear. The purpose of this study w...

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Bibliographic Details
Main Authors: Julian Fauß, Bettina Sprang, Petra Leukel, Clemens Sommer, Teodora Nikolova, Florian Ringel, Ella L. Kim
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
glioblastoma
glioma stem cells
ALDH1
protein turnover
proteasomal degradation
Online Access:https://www.mdpi.com/2227-9059/10/1/7

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https://www.mdpi.com/2227-9059/10/1/7

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