Highly selective whole-cell 25-hydroxyvitamin D3 synthesis using molybdenum-dependent C25-steroid dehydrogenase and cyclodextrin recycling

Highly selective whole-cell 25-hydroxyvitamin D3 synthesis using molybdenum-dependent C25-steroid dehydrogenase and cyclodextrin recycling

Abstract Background The global prevalence of vitamin D (VitD) deficiency associated with numerous acute and chronic diseases has led to strategies to improve the VitD status through dietary intake of VitD-fortified foods and VitD supplementation. In this context, the circulating form of VitD3 (chole...

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Bibliographic Details
Main Authors: Dennis Kosian, Max Willistein, Ralf Weßbecher, Constantin Eggers, Oliver May, Matthias Boll
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Microbial Cell Factories
Subjects:
Vitamin D3
25-hydroxyvitamin D3
Calcifediol
Calcitriol
Whole-cell biocatalysis
Thauera aromatica
Online Access:https://doi.org/10.1186/s12934-024-02303-6

Internet

https://doi.org/10.1186/s12934-024-02303-6

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