Maternal high-fat diet promotes calcified atherosclerotic plaque formation in adult offspring by enhancing transformation of VSMCs to osteochondrocytic-like phenotype

Maternal high-fat diet promotes calcified atherosclerotic plaque formation in adult offspring by enhancing transformation of VSMCs to osteochondrocytic-like phenotype

Aim: Maternal high-fat diet (HFD) is associated with the development of cardiovascular disease (CVD) in adult offspring. Atherosclerotic vascular calcification is well documented in patients with CVD. We examined the effect of maternal HFD on calcified plaque formation. Methods and results: Seven-we...

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Bibliographic Details
Main Authors: Daisuke Miyawaki, Hiroyuki Yamada, Makoto Saburi, Naotoshi Wada, Shinichiro Motoyama, Takeshi Sugimoto, Hiroshi Kubota, Noriyuki Wakana, Daisuke Kami, Takehiro Ogata, Satoaki Matoba
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Heliyon
Subjects:
Maternal high-fat diet
Atherosclerosis
Cardiovascular calcification
Interleukin-1β
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022019326

Internet

http://www.sciencedirect.com/science/article/pii/S2405844022019326

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