PTC124 Rescues Nonsense Mutation of Two Tumor Suppressor Genes <i>NOTCH1</i> and <i>FAT1</i> to Repress HNSCC Cell Proliferation
(1) Background: PTC124 (Ataluren) is an investigational drug for the treatment of nonsense mutation-mediated genetic diseases. With the exception of the <i>TP53</i> tumor suppressor gene, there has been little research on cancers with nonsense mutation. By conducting a database search, w...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
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| Series: | Biomedicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/10/11/2948 |