Biliary Obstruction Promotes Multilineage Differentiation of Hepatic Stem Cells

Because of their high regenerative potential, stem cells are an ideal resource for development of therapies that replace injured tissue mass and restore function in patients with end‐stage liver diseases. Using a rat model of bile duct ligation (BDL) and biliary fibrosis, we investigated cell engraf...

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Bibliographic Details
Main Authors: Mladen I. Yovchev, Edward J. Lee, Waldemar Rodriguez‐Silva, Joseph Locker, Michael Oertel
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2019-08-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1367