Heat shock protein 70/peptide complexes: potent mediators for the generation of antiviral T cells particularly with regard to low precursor frequencies

<p>Abstract</p> <p>Background</p> <p>Heat shock protein 70 (HSP70) has gained major attention as an adjuvant capable of inducing antigen-specific CD8<sup>+ </sup>and CD4<sup>+ </sup>T-cell responses. The ability of HSP70/peptide complexes to elic...

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Bibliographic Details
Main Authors: Immenschuh Stephan, Maecker-Kolhoff Britta, Basila Megan, Tischer Sabine, Oelke Mathias, Blasczyk Rainer, Eiz-Vesper Britta
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/175