Identification of transglutaminase reactive residues in human osteopontin and their role in polymerization.

Osteopontin (OPN) is a highly posttranslationally modified protein present in several tissues where it is implicated in numerous physiological processes. OPN primarily exerts its functions through interaction with integrins via the Arg-Gly-Asp and Ser-Val-Val-Tyr-Gly-Leu-Arg sequences located in the...

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Bibliographic Details
Main Authors: Brian Christensen, Elias D Zachariae, Carsten Scavenius, Morten Thybo, Morten M Callesen, Søren Kløverpris, Claus Oxvig, Jan J Enghild, Esben S Sørensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4242673?pdf=render