Identification of RNA reads encoding different channels in isolated rat ventricular myocytes and the effect of cell stretching on L-type Ca 2+ current

Identification of RNA reads encoding different channels in isolated rat ventricular myocytes and the effect of cell stretching on L-type Ca 2+ current

Abstract Background The study aimed to identify transcripts of specific ion channels in rat ventricular cardiomyocytes and determine their potential role in the regulation of ionic currents in response to mechanical stimulation. The gene expression levels of various ion channels in freshly isolated...

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Bibliographic Details
Main Authors: Andre G. Kamkin, Olga V. Kamkina, Viktor E. Kazansky, Vadim M. Mitrokhin, Andrey Bilichenko, Elizaveta A. Nasedkina, Stanislav A. Shileiko, Anastasia S. Rodina, Alexandra D. Zolotareva, Valentin I. Zolotarev, Pavel V. Sutyagin, Mitko I. Mladenov
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Biology Direct
Subjects:
Rat ventricular myocytes
Mechanosensitive cation channels
Stretch-activated channels
mRNA
Transcriptomic profile
CaV1.2 channels
Online Access:https://doi.org/10.1186/s13062-023-00427-0

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https://doi.org/10.1186/s13062-023-00427-0

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