Major Vault Protein (MVP) Associated With BRAFV600E Mutation Is an Immune Microenvironment-Related Biomarker Promoting the Progression of Papillary Thyroid Cancer via MAPK/ERK and PI3K/AKT Pathways

Major Vault Protein (MVP) Associated With BRAFV600E Mutation Is an Immune Microenvironment-Related Biomarker Promoting the Progression of Papillary Thyroid Cancer via MAPK/ERK and PI3K/AKT Pathways

Papillary thyroid cancer (PTC) is the most common malignancy of the endocrine system, with an increase in incidence frequency. Major vault protein (MVP) is the main structural protein of the vault complex that has already been investigated in specific cancers. Yet the underlying biological functions...

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Bibliographic Details
Main Authors: Xubin Dong, Percy David Papa Akuetteh, Jingjing Song, Chao Ni, Cong Jin, Huihui Li, Wenjie Jiang, Yuhao Si, Xiaohua Zhang, Qiyu Zhang, Guanli Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
major vault protein
papillary thyroid cancer
biomarker
tumor microenvironment
BRAFV600E
RAS
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.688370/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.688370/full

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