Human mid-trimester amniotic fluid (stem) cells lack expression of the pluripotency marker OCT4A

Abstract Expression of OCT4A is one of the hallmarks of pluripotency, defined as a stem cell’s ability to differentiate into all the lineages of the three germ layers. Despite being defined as non-tumorigenic cells with high translational potential, human mid-trimester amniotic fluid stem cells (hAF...

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Bibliographic Details
Main Authors: Filipa Vlahova, Kate E. Hawkins, Anna Maria Ranzoni, Kwan-Leong Hau, Rachel Sagar, Paolo De Coppi, Anna L. David, James Adjaye, Pascale V. Guillot
Format: Article
Language:English
Published: Nature Portfolio 2019-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-44572-x