Non-catalytic functions of Pyk2 and Fyn regulate late stage adhesion in human T cells.

T cell activation drives the protective immune response against pathogens, but is also critical for the development of pathological diseases in humans. Cytoskeletal changes are required for downstream functions in T cells, including proliferation, cytokine production, migration, spreading, and adhes...

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Bibliographic Details
Main Authors: Nicole M Chapman, Ashley N Yoder, Jon C D Houtman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3531412?pdf=render