Empirical relationship between intra-purine and intra-pyrimidine differences in conserved gene sequences.
DNA sequences seen in the normal character-based representation appear to have a formidable mixing of the four nucleotides without any apparent order. Nucleotide frequencies and distributions in the sequences have been studied extensively, since the simple rule given by Chargaff almost a century ago...
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Format: | Article |
Language: | English |
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Public Library of Science (PLoS)
2009-08-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2730015?pdf=render |