Is <i>N</i>1-Methylnicotinamide a Good Organic Cation Transporter 2 (OCT2) Biomarker?

Is <i>N</i>1-Methylnicotinamide a Good Organic Cation Transporter 2 (OCT2) Biomarker?

<b>Background/Objectives:</b> The impact of potential precipitant drugs on plasma or urinary exposure of endogenous biomarkers is emerging as an alternative approach to evaluating drug–drug interaction (DDI) liability. <i>N</i>1-Methylnicotinamide (NMN) has been proposed as a...

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Bibliographic Details
Main Authors: Anoud Sameer Ailabouni, Gautam Vijaywargi, Sandhya Subash, Dilip Kumar Singh, Zsuzsanna Gaborik, Bhagwat Prasad
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Metabolites
Subjects:
renal transport
hepatic transport
organic cation transport
pharmacokinetic
drug–drug interactions
endogenous biomarkers
Online Access:https://www.mdpi.com/2218-1989/15/2/80

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https://www.mdpi.com/2218-1989/15/2/80

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