Reversing the directionality of reactions between non-oxidative pentose phosphate pathway and glycolytic pathway boosts mycosporine-like amino acid production in Saccharomyces cerevisiae

Reversing the directionality of reactions between non-oxidative pentose phosphate pathway and glycolytic pathway boosts mycosporine-like amino acid production in Saccharomyces cerevisiae

Abstract Background Mycosporine-like amino acids (MAAs) are a class of strongly UV-absorbing compounds produced by cyanobacteria, algae and corals and are promising candidates for natural sunscreen components. Low MAA yields from natural sources, coupled with difficulties in culturing its native pro...

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Bibliographic Details
Main Authors: Miselle Tiana Hengardi, Cui Liang, Keshiniy Madivannan, Lay Kien Yang, Lokanand Koduru, Yoganathan Kanagasundaram, Prakash Arumugam
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Microbial Cell Factories
Subjects:
Saccharomyces cerevisiae
Metabolic engineering
Mycosporine-like amino acids
Metabolic pathway
Reversed non-oxidative pentose phosphate pathway
Online Access:https://doi.org/10.1186/s12934-024-02365-6

Internet

https://doi.org/10.1186/s12934-024-02365-6

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