A Loading Dose of Dexmedetomidine With Constant Infusion Inhibits Intraoperative Neuromonitoring During Thoracic Spinal Decompression Surgery: A Randomized Prospective Study

A Loading Dose of Dexmedetomidine With Constant Infusion Inhibits Intraoperative Neuromonitoring During Thoracic Spinal Decompression Surgery: A Randomized Prospective Study

Background: The effect of a bolus dose of dexmedetomidine on intraoperative neuromonitoring (IONM) parameters during spinal surgeries has been variably reported and remains a debated topic.Methods: A randomized, double-blinded, placebo-controlled study was performed to assess the effect of dexmedeto...

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Bibliographic Details
Main Authors: Tun Liu, Yue Qin, Huaguang Qi, Zhenguo Luo, Liang Yan, Pengfei Yu, Buhuai Dong, Songchuan Zhao, Xucai Wu, Zhen Chang, Zhian Liu, Xuemei Liu, Tao Yuan, Houkun Li, Li Xiao, Gang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pharmacology
Subjects:
dexmedetomidine
intraoperative neuromonitoring
thoracic spinal decompression surgery
motor evoked potential (MEP)
somatosensory evoked potential (SSEP)
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.840320/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.840320/full

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