Whi5 regulation by site specific CDK-phosphorylation in Saccharomyces cerevisiae.

Whi5 regulation by site specific CDK-phosphorylation in Saccharomyces cerevisiae.

The Whi5 transcriptional repressor is a negative regulator of G1 cell cycle progression in Saccharomyces cerevisiae and is functionally equivalent to the Retinoblastoma (Rb) tumor suppressor protein in mammals. In early G1, Whi5 binds to and inhibits SBF (Swi4/Swi6) transcriptional complexes. At Sta...

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Bibliographic Details
Main Authors: Michelle V Wagner, Marcus B Smolka, Rob A M de Bruin, Huilin Zhou, Curt Wittenberg, Steven F Dowdy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2627923?pdf=render

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http://europepmc.org/articles/PMC2627923?pdf=render

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