Galectin-9 and Interferon-Gamma Are Released by Natural Killer Cells upon Activation with Interferon-Alpha and Orchestrate the Suppression of Hepatitis C Virus Infection

Galectin-9 and Interferon-Gamma Are Released by Natural Killer Cells upon Activation with Interferon-Alpha and Orchestrate the Suppression of Hepatitis C Virus Infection

Natural killer (NK) cells mount an immune response against hepatitis C virus (HCV) infection and can be activated by several cytokines, including interleukin-2 (IL-2), IL-15, and interferon-alpha (IFN-α). By exploiting the Huh7.5 hepatoma cell line infected with the HCV JFH1 genome, we provide novel...

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Bibliographic Details
Main Authors: Anna Paola Carreca, Massimiliano Gaetani, Rosalia Busà, Maria Giovanna Francipane, Maria Rita Gulotta, Ugo Perricone, Gioacchin Iannolo, Giovanna Russelli, Claudia Carcione, Pier Giulio Conaldi, Ester Badami
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
HCV
NK cells
IFN-α
galectin-9
IFN-γ
Online Access:https://www.mdpi.com/1999-4915/14/7/1538

Internet

https://www.mdpi.com/1999-4915/14/7/1538

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