Effects of heme oxygenase-1 on innate and adaptive immune responses promoting pregnancy success and allograft tolerance
The heme-degrading enzyme heme oxygenase-1 (HO-1) has cytoprotective, antioxidant and anti-inflammatory properties. Moreover, HO-1 is reportedly involved in suppressing destructive immune responses associated with inflammation, autoimmune diseases, and allograft rejection. During pregnancy, maternal...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-01-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00288/full |