Effects of heme oxygenase-1 on innate and adaptive immune responses promoting pregnancy success and allograft tolerance

Effects of heme oxygenase-1 on innate and adaptive immune responses promoting pregnancy success and allograft tolerance

The heme-degrading enzyme heme oxygenase-1 (HO-1) has cytoprotective, antioxidant and anti-inflammatory properties. Moreover, HO-1 is reportedly involved in suppressing destructive immune responses associated with inflammation, autoimmune diseases, and allograft rejection. During pregnancy, maternal...

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Bibliographic Details
Main Authors:	Anne eSchumacher, Ana Claudia Zenclussen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-01-01
Series:	Frontiers in Pharmacology
Subjects:	Heme Oxygenase-1 Immune Tolerance Pregnancy allograft allo-antigens
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00288/full

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