NEDD9 Facilitates Hypoxia-Induced Gastric Cancer Cell Migration via MICAL1 Related Rac1 Activation

NEDD9 Facilitates Hypoxia-Induced Gastric Cancer Cell Migration via MICAL1 Related Rac1 Activation

Aims and Hypothesis: NEDD9 is highly expressed in gastric cancer and has a significant involvement in its pathogenesis. However, the mechanism behind hypoxia-promoted cancer cell migration and its regulation because of NEDD9 is still unknown. The aim of this study is to investigate the involvement o...

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Bibliographic Details
Main Authors: Shuo Zhao, Pengxiang Min, Lei Liu, Lin Zhang, Yujie Zhang, Yueyuan Wang, Xuyang Zhao, Yadong Ma, Hui Xie, Chenchen Zhu, Haonan Jiang, Jun Du, Luo Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
MICAL1
NEDD9
migration
gastric cancer
Rac1
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00291/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00291/full

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