Long non‐coding RNA PCAT6 targets miR‐204 to modulate the chemoresistance of colorectal cancer cells to 5‐fluorouracil‐based treatment through HMGA2 signaling

Long non‐coding RNA PCAT6 targets miR‐204 to modulate the chemoresistance of colorectal cancer cells to 5‐fluorouracil‐based treatment through HMGA2 signaling

Abstract Colorectal cancer (CRC) is still the third most common cancer in the world with a limited prognosis due to the chemoresistance of CRC cells to 5‐fluorouracil (5‐FU)‐based chemotherapy. In our previous study, we revealed that miR‐204 overexpression could sensitize CRC cell to 5‐FU treatment...

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Bibliographic Details
Main Authors: Haijun Wu, Qiongyan Zou, Hong He, Yu Liang, Mingjun Lei, Qin Zhou, Dan Fan, Liangfang Shen
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Cancer Medicine
Subjects:
5‐fluorouracil
chemoresistance
colorectal cancer
HMGA2
lncRNA prostate cancer‐associated transcript 6
miR‐204
Online Access:https://doi.org/10.1002/cam4.1809

Internet

https://doi.org/10.1002/cam4.1809

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