Network-based quantitative trait linkage analysis of microbiome composition in inflammatory bowel disease families

Network-based quantitative trait linkage analysis of microbiome composition in inflammatory bowel disease families

Introduction: Inflammatory bowel disease (IBD) is characterized by a dysbiosis of the gut microbiome that results from the interaction of the constituting taxa with one another, and with the host. At the same time, host genetic variation is associated with both IBD risk and microbiome composition.Me...

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Bibliographic Details
Main Authors: Arunabh Sharma, Olaf Junge, Silke Szymczak, Malte Christoph Rühlemann, Janna Enderle, Stefan Schreiber, Matthias Laudes, Andre Franke, Wolfgang Lieb, Michael Krawczak, Astrid Dempfle
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
linkage analysis
gut microbiome
inflammatory bowel disease
family-based study design
microbiome co-occurrence network
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1048312/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1048312/full

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