Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology
Kolloli et al. examine whether aggregation contributes to enhanced pathogenicity of Mycobacterium tuberculosis in a rabbit model of pulmonary infection. They demonstrate that aggregation increases the ability of M. tuberculosis to grow robustly and promote inflammation and host cell death in the rab...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02769-9 |