Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology

Kolloli et al. examine whether aggregation contributes to enhanced pathogenicity of Mycobacterium tuberculosis in a rabbit model of pulmonary infection. They demonstrate that aggregation increases the ability of M. tuberculosis to grow robustly and promote inflammation and host cell death in the rab...

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Bibliographic Details
Main Authors: Afsal Kolloli, Ranjeet Kumar, Pooja Singh, Anshika Narang, Gilla Kaplan, Alex Sigal, Selvakumar Subbian
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02769-9