Modeling RET-Rearranged Non-Small Cell Lung Cancer (NSCLC): Generation of Lung Progenitor Cells (LPCs) from Patient-Derived Induced Pluripotent Stem Cells (iPSCs)

Modeling RET-Rearranged Non-Small Cell Lung Cancer (NSCLC): Generation of Lung Progenitor Cells (LPCs) from Patient-Derived Induced Pluripotent Stem Cells (iPSCs)

REarranged during Transfection (RET) oncogenic rearrangements can occur in 1–2% of lung adenocarcinomas. While RET-driven NSCLC models have been developed using various approaches, no model based on patient-derived induced pluripotent stem cells (iPSCs) has yet been described. Patient-derived iPSCs...

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Bibliographic Details
Main Authors: Paul Marcoux, Jin Wook Hwang, Christophe Desterke, Jusuf Imeri, Annelise Bennaceur-Griscelli, Ali G. Turhan
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
NSCLC
patient derived
iPSCs
RET
LPC differentiation
cancer
Online Access:https://www.mdpi.com/2073-4409/12/24/2847

Internet

https://www.mdpi.com/2073-4409/12/24/2847

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