Calibrating Seed-Based Heuristics to Map Short Reads With Sesame

The increasing throughput of DNA sequencing technologies creates a need for faster algorithms. The fate of most reads is to be mapped to a reference sequence, typically a genome. Modern mappers rely on heuristics to gain speed at a reasonable cost for accuracy. In the seeding heuristic, short matche...

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Bibliographic Details
Main Authors: Guillaume J. Filion, Ruggero Cortini, Eduard Zorita
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00572/full