N6-methyladenosine modification of circular RNA circASH2L suppresses growth and metastasis in hepatocellular carcinoma through regulating hsa-miR-525-3p/MTUS2 axis

N6-methyladenosine modification of circular RNA circASH2L suppresses growth and metastasis in hepatocellular carcinoma through regulating hsa-miR-525-3p/MTUS2 axis

Abstract Background CircRNAs have been demonstrated to play a crucial role in regulating the growth and progression of various cancers, including hepatocellular carcinoma (HCC). Nevertheless, the circRNA's expression pattern and function in HCC need more investigation. Methods Bioinformatics te...

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Bibliographic Details
Main Authors: Dafeng Xu, Yachong Liu, Qiumeng Liu, Ganxun Li, Lu Zhang, Chengpeng Yu, Huifang Liang, Xiaoping Chen, Jinfang Zheng, Jia Song
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Circular RNA
CircASH2L
HCC
MiR-525-3p
MTUS2
METTL3
Online Access:https://doi.org/10.1186/s12967-024-05745-z

Internet

https://doi.org/10.1186/s12967-024-05745-z

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