VX-765 inhibits pyroptosis and reduces inflammation to prevent acute liver failure by upregulating PPARα expression
Introduction and Objectives: As a fatal clinical syndrome, acute liver failure (ALF) is characterized by overwhelming liver inflammation and hepatic cell death. Finding new therapeutic methods has been a challenge in ALF research. VX-765 is a known pyroptosis inhibitor and has been reported to preve...
Main Authors: | Mingjing Jiao, Jiachao Wang, Wenpeng Liu, Xin Zhao, Yanjun Qin, Chunhuan Zhang, Hongzhu Yin, Caiyan Zhao |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-05-01
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Series: | Annals of Hepatology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268123001862 |
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