Intragenic recombination has a critical role on the evolution of Legionella pneumophila virulence-related effector sidJ.

SidJ is a Dot/Icm effector involved in the trafficking or retention of ER-derived vesicles to Legionella pneumophila vacuoles whose mutation causes an observable growth defect, both in macrophage and amoeba hosts. Given the crucial role of this effector in L. pneumophila virulence we investigated th...

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Bibliographic Details
Main Authors: Joana Costa, Paulo Gonçalves Teixeira, Ana Filipa d'Avó, Célio Santos Júnior, António Veríssimo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4192588?pdf=render