Intragenic recombination has a critical role on the evolution of Legionella pneumophila virulence-related effector sidJ.

SidJ is a Dot/Icm effector involved in the trafficking or retention of ER-derived vesicles to Legionella pneumophila vacuoles whose mutation causes an observable growth defect, both in macrophage and amoeba hosts. Given the crucial role of this effector in L. pneumophila virulence we investigated th...

Descripción completa

Detalles Bibliográficos
Autores principales: Joana Costa, Paulo Gonçalves Teixeira, Ana Filipa d'Avó, Célio Santos Júnior, António Veríssimo
Formato: Artículo
Lenguaje:English
Publicado: Public Library of Science (PLoS) 2014-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4192588?pdf=render