Paclitaxel chemotherapy disrupts microbiota-enterohepatic bile acid metabolism in mice

Balanced interactions between the enteric microbiota and enterohepatic organs are essential to bile acid homeostasis, and thus normal gastrointestinal function. Disruption of these interactions by cancer treatment instigates bile acid malabsorption, leading to treatment delays, malnutrition, and dec...

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Bibliographic Details
Main Authors: Brett R. Loman, Zainab Alzoubi, Alexis J. Lynch, Robert M. Jaggers, Kelley Jordan, Corena V. Grant, Lynette K. Rogers, Leah M. Pyter, Michael T. Bailey
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Gut Microbes
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2410475