Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement

Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement

Abstract Background There is growing recognition that bidirectional signaling between the digestive tract and the brain contributes to irritable bowel syndrome (IBS). We recently showed in a large randomized controlled trial that cognitive behavioral therapy (CBT) reduces IBS symptom severity. This...

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Bibliographic Details
Main Authors: Jonathan P. Jacobs, Arpana Gupta, Ravi R. Bhatt, Jacob Brawer, Kan Gao, Kirsten Tillisch, Venu Lagishetty, Rebecca Firth, Gregory D. Gudleski, Benjamin M. Ellingson, Jennifer S. Labus, Bruce D. Naliboff, Jeffrey M. Lackner, Emeran A. Mayer
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Microbiome
Subjects:
Cognitive behavioral therapy
Irritable bowel syndrome
Brain-gut-microbiome axis
Neuroimaging
Biomarkers
Outcome prediction
Online Access:https://doi.org/10.1186/s40168-021-01188-6

Internet

https://doi.org/10.1186/s40168-021-01188-6

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