Early onset obesity due to a mutation in the human leptin receptor gene
Leptin is secreted by adipocytes in response to fat storage and binds to its receptor (LEPR), which is ubiquitously expressed throughout the body. Leptin regulates energy expenditure and is anorexigenic. In this study, we describe the clinical and hormonal findings of three siblings with a personal...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bioscientifica
2022-08-01
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| Series: | Endocrine Connections |
| Online Access: | https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM21-0124.xml |