ADP-Ribosylation of NLRP3 by <named-content content-type="genus-species">Mycoplasma pneumoniae</named-content> CARDS Toxin Regulates Inflammasome Activity
ABSTRACT The inflammasome is a major regulator of inflammation through its activation of procaspase-1, which cleaves prointerleukin-1β (pro-IL-1β) into its mature form. IL-1β is a critical proinflammatory cytokine that dictates the severity of inflammation associated with a wide spectrum of inflamma...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2014-12-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.02186-14 |