Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies

Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies

Abstract Background To investigate the anti-inflammatory and antioxidative effects of gallic acid (GA) on human corneal epithelial cells (HCECs) and RAW264.7 macrophages as well as its therapeutic effects in an experimental dry eye (EDE) mouse model. Methods A cell counting kit-8 (CCK-8) assay was u...

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Bibliographic Details
Main Authors: Kexin Li, Qianwen Gong, Bin Lu, Kaiyan Huang, Yixuan Tong, Tinashe Emmanuel Mutsvene, Meng Lin, Zhiqiang Xu, Fan Lu, Xingyi Li, Liang Hu
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Eye and Vision
Subjects:
Corneal epithelial cells
Macrophages
Gallic acid
Dry eye
Inflammation
Oxidative stress
Online Access:https://doi.org/10.1186/s40662-023-00334-5

Internet

https://doi.org/10.1186/s40662-023-00334-5

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