Molecular mechanisms of inhibitor of growth (ING) family members in health and malignancy

Molecular mechanisms of inhibitor of growth (ING) family members in health and malignancy

Abstract ING genes belong to family of tumor suppressor genes with regulatory functions on cell proliferation, apoptosis, and cellular senescence. These include a family of proteins with 5 members (ING1-5), which are downregulated in human malignancies and/or affected by pathogenic mutations. ING pr...

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Bibliographic Details
Main Authors: Mohammad Taheri, Bashdar Mahmud Hussen, Sajad Najafi, Atefe Abak, Soudeh Ghafouri-Fard, Majid Samsami, Aria Baniahmad
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cancer Cell International
Subjects:
ING
Tumor suppressor gene
Cancer
Oncogene
Cellular senescence
Splice variants
Online Access:https://doi.org/10.1186/s12935-022-02693-w

Internet

https://doi.org/10.1186/s12935-022-02693-w

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