Multiple Myeloma With Amplification of Chr1q: Therapeutic Opportunity and Challenges

Multiple myeloma (MM) is an incurable plasma cell malignancy with a heterogeneous genetic background. Each MM subtype may have its own therapeutic vulnerabilities, and tailored therapy could improve outcomes. However, the cumulative frequency of druggable targets across patients is very low, which h...

Full description

Bibliographic Details
Main Authors: Romanos Sklavenitis-Pistofidis, Gad Getz, Irene Ghobrial, Maria Papaioannou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.961421/full