Influence of the sickle cell trait on Plasmodium falciparum infectivity from naturally infected gametocyte carriers

Influence of the sickle cell trait on Plasmodium falciparum infectivity from naturally infected gametocyte carriers

Abstract Background Sickle cell trait (SCT) refers to the carriage of one abnormal copy of the β-globin gene, the HbS allele. SCT offers protection against malaria, controlling parasite density and preventing progression to symptomatic malaria. However, it remains unclear whether SCT also affects tr...

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Bibliographic Details
Main Authors: Christelle M. Ngou, Albert N. Bayibéki, Luc Abate, Olesula S. Makinde, Lionel B. Feufack-Donfack, Elangwe M. Sarah-Matio, Aline G. Bouopda-Tuedom, Paul Taconet, Nicolas Moiroux, Parfait H. Awono-Ambéné, Arthur Talman, Lawrence S. Ayong, Antoine Berry, Sandrine E. Nsango, Isabelle Morlais
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Infectious Diseases
Subjects:
Sickle cell trait
Asymptomatic carriers
Malaria transmission
Mosquito infectivity
Gametocytes
Online Access:https://doi.org/10.1186/s12879-023-08134-x

Internet

https://doi.org/10.1186/s12879-023-08134-x

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