Influence of the sickle cell trait on Plasmodium falciparum infectivity from naturally infected gametocyte carriers
Abstract Background Sickle cell trait (SCT) refers to the carriage of one abnormal copy of the β-globin gene, the HbS allele. SCT offers protection against malaria, controlling parasite density and preventing progression to symptomatic malaria. However, it remains unclear whether SCT also affects tr...
Main Authors: | Christelle M. Ngou, Albert N. Bayibéki, Luc Abate, Olesula S. Makinde, Lionel B. Feufack-Donfack, Elangwe M. Sarah-Matio, Aline G. Bouopda-Tuedom, Paul Taconet, Nicolas Moiroux, Parfait H. Awono-Ambéné, Arthur Talman, Lawrence S. Ayong, Antoine Berry, Sandrine E. Nsango, Isabelle Morlais |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-05-01
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Series: | BMC Infectious Diseases |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12879-023-08134-x |
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