Mesenchymal stem cells empower T cells in the lymph nodes via MCP-1/PD-L1 axis

Mesenchymal stem cells empower T cells in the lymph nodes via MCP-1/PD-L1 axis

Abstract Mesenchymal stem cells (MSCs) are a type of immunosuppressive stromal cell found in multiple tissues and organs. However, whether MSCs possess immunosupportive characteristics remains unclear. In this study, we showed that the lymph nodes contain immunosupportive MSCs. They produce and secr...

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Bibliographic Details
Main Authors: Yifan He, Yan Qu, Bowen Meng, Weiying Huang, Jianxia Tang, Runci Wang, Zetao Chen, Xiaoxing Kou, Songtao Shi
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04822-9

Internet

https://doi.org/10.1038/s41419-022-04822-9

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