Icariside II Exerts Anti-Type 2 Diabetic Effect by Targeting PPARα/γ: Involvement of ROS/NF-κB/IRS1 Signaling Pathway

Icariside II Exerts Anti-Type 2 Diabetic Effect by Targeting PPARα/γ: Involvement of ROS/NF-κB/IRS1 Signaling Pathway

Type 2 diabetes mellitus (T2DM) is a multisystem and complex metabolic disorder which is associated with insulin resistance and impairments of pancreatic β-cells. Previous studies have shown that icariside II (ICS II), one of the main active ingredients of <i>Herba Epimedii</i>, exerts p...

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Bibliographic Details
Main Authors: Yiqi Li, Yeli Li, Nana Chen, Linying Feng, Jianmei Gao, Nan Zeng, Zhixu He, Qihai Gong
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antioxidants
Subjects:
Icariside II
Type 2 diabetes mellitus
peroxisome proliferator-activated receptors α and γ
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2076-3921/11/9/1705

Internet

https://www.mdpi.com/2076-3921/11/9/1705

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