Epigenetic and genetic alterations affect the WWOX gene in head and neck squamous cell carcinoma.

Different types of genetic and epigenetic changes are associated with HNSCC. The molecular mechanisms of HNSCC carcinogenesis are still undergoing intensive investigation. WWOX gene expression is altered in many cancers and in a recent work reduced WWOX expression has been associated with miR-134 ex...

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Bibliographic Details
Main Authors: Seda Ekizoglu, Pelin Bulut, Emin Karaman, Erkan Kilic, Nur Buyru
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4303423?pdf=render