Whole Exome Sequencing Enhanced Imputation Identifies 85 Metabolite Associations in the Alpine CHRIS Cohort

Whole Exome Sequencing Enhanced Imputation Identifies 85 Metabolite Associations in the Alpine CHRIS Cohort

Metabolites are intermediates or end products of biochemical processes involved in both health and disease. Here, we take advantage of the well-characterized Cooperative Health Research in South Tyrol (CHRIS) study to perform an exome-wide association study (ExWAS) on absolute concentrations of 175...

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Bibliographic Details
Main Authors: Eva König, Johannes Rainer, Vinicius Verri Hernandes, Giuseppe Paglia, Fabiola Del Greco M., Daniele Bottigliengo, Xianyong Yin, Lap Sum Chan, Alexander Teumer, Peter P. Pramstaller, Adam E. Locke, Christian Fuchsberger
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Metabolites
Subjects:
GWAS
ExWAS
association study
whole-exome sequencing
imputation
metabolomics
Online Access:https://www.mdpi.com/2218-1989/12/7/604

Internet

https://www.mdpi.com/2218-1989/12/7/604

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