Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.

Due to recent advances of bioinformatics and high throughput sequencing technology, discovery of regulatory noncoding RNAs in bacteria has been increased to a great extent. Based on this bandwagon, many studies searching for trans-acting small noncoding RNAs in streptococci have been performed inten...

Full description

Bibliographic Details
Main Authors: Kyu Hong eCho, Jeong-Ho eKim
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00110/full
_version_ 1817998746536902656
author Kyu Hong eCho
Jeong-Ho eKim
author_facet Kyu Hong eCho
Jeong-Ho eKim
author_sort Kyu Hong eCho
collection DOAJ
description Due to recent advances of bioinformatics and high throughput sequencing technology, discovery of regulatory noncoding RNAs in bacteria has been increased to a great extent. Based on this bandwagon, many studies searching for trans-acting small noncoding RNAs in streptococci have been performed intensively, especially in the important human pathogen, group A and B streptococci. However, studies for cis-encoded noncoding antisense RNAs in streptococci have been scarce. A recent study shows antisense RNAs are involved in virulence gene regulation in group B streptococcus, S. agalactiae. This suggests antisense RNAs could have important roles in the pathogenesis of streptococcal pathogens. In this review, we describe recent discoveries of chromosomal cis-encoded antisense RNAs in streptococcal pathogens and other low GC Gram (+) bacteria to provide a guide for future studies.
first_indexed 2024-04-14T02:57:04Z
format Article
id doaj.art-9224277dd9504e5ca0bdc17d6d105130
institution Directory Open Access Journal
issn 1664-8021
language English
last_indexed 2024-04-14T02:57:04Z
publishDate 2015-03-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Genetics
spelling doaj.art-9224277dd9504e5ca0bdc17d6d1051302022-12-22T02:16:02ZengFrontiers Media S.A.Frontiers in Genetics1664-80212015-03-01610.3389/fgene.2015.00110134045Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.Kyu Hong eCho0Jeong-Ho eKim1Indiana State UniversityThe George Washington University Medical CenterDue to recent advances of bioinformatics and high throughput sequencing technology, discovery of regulatory noncoding RNAs in bacteria has been increased to a great extent. Based on this bandwagon, many studies searching for trans-acting small noncoding RNAs in streptococci have been performed intensively, especially in the important human pathogen, group A and B streptococci. However, studies for cis-encoded noncoding antisense RNAs in streptococci have been scarce. A recent study shows antisense RNAs are involved in virulence gene regulation in group B streptococcus, S. agalactiae. This suggests antisense RNAs could have important roles in the pathogenesis of streptococcal pathogens. In this review, we describe recent discoveries of chromosomal cis-encoded antisense RNAs in streptococcal pathogens and other low GC Gram (+) bacteria to provide a guide for future studies.http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00110/fullnoncoding RNAsregulatory RNAsstreptococciAntisense RNAsGram (+) pathogens
spellingShingle Kyu Hong eCho
Jeong-Ho eKim
Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.
Frontiers in Genetics
noncoding RNAs
regulatory RNAs
streptococci
Antisense RNAs
Gram (+) pathogens
title Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.
title_full Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.
title_fullStr Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.
title_full_unstemmed Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.
title_short Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.
title_sort cis encoded noncoding antisense rnas in streptococci and other low gc gram bacterial pathogens
topic noncoding RNAs
regulatory RNAs
streptococci
Antisense RNAs
Gram (+) pathogens
url http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00110/full
work_keys_str_mv AT kyuhongecho cisencodednoncodingantisensernasinstreptococciandotherlowgcgrambacterialpathogens
AT jeonghoekim cisencodednoncodingantisensernasinstreptococciandotherlowgcgrambacterialpathogens