Conserved Residues Lys64 and Glu78 at the Subunit Surface of Tau Glutathione Transferase in Rice Affect Structure and Enzymatic Properties

Conserved Residues Lys64 and Glu78 at the Subunit Surface of Tau Glutathione Transferase in Rice Affect Structure and Enzymatic Properties

Glutathione transferases (GSTs) are a superfamily of dimeric proteins associated with the detoxification of various reactive electrophiles and responsive to a multitude of stressors. We individually substituted Lys64 and Glu78 with Ala using site-directed mutagenesis to understand the role of subuni...

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Bibliographic Details
Main Authors: Xue Yang, Zhe Zhang, Lei Wu, Meiying Yang, Siyuan Li, Jie Gao
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
glutathione transferases
hydrogen bond
ionic bond
site-directed mutagenesis
structural changes
activity changes
Online Access:https://www.mdpi.com/1422-0067/25/1/398

Internet

https://www.mdpi.com/1422-0067/25/1/398

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