Synthesis and Evaluation of a <sup>18</sup>F-Labeled Ligand for PET Imaging of Colony-Stimulating Factor 1 Receptor

Synthesis and Evaluation of a <sup>18</sup>F-Labeled Ligand for PET Imaging of Colony-Stimulating Factor 1 Receptor

Neuroinflammation involves activation of glial cells in the brain, and activated microglia play a particularly important role in neurodegenerative diseases such as Alzheimer’s disease (AD). In this study, we developed 5-cyano-<i>N</i>-(4-(4-(2-[<sup>18</sup>F]fluoroethyl)pipe...

Full description

Bibliographic Details
Main Authors: Hyeokjin Lee, Ji-Hun Park, Hyunjung Kim, Sang-keun Woo, Joon Young Choi, Kyung-Han Lee, Yearn Seong Choe
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceuticals
Subjects:
colony-stimulating factor 1 receptor
neuroinflammation
microglia
PET
<sup>18</sup>F
CPPC
Online Access:https://www.mdpi.com/1424-8247/15/3/276

Internet

https://www.mdpi.com/1424-8247/15/3/276

Similar Items