MicroRNA dysregulation, gene networks and risk for schizophrenia in 22q11.2 deletion syndrome

MicroRNA dysregulation, gene networks and risk for schizophrenia in 22q11.2 deletion syndrome

The role of microRNAs (miRNAs) in the aetiology of schizophrenia is increasingly recognized. Microdeletions at chromosome 22q11.2 are recurrent structural variants that impart a high risk for schizophrenia and are found in up to 1% of all patients with schizophrenia. The 22q11.2 deletion region over...

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Bibliographic Details
Main Authors: Daniele eMerico, Gregory eCostain, Nancy eButcher, William eWarnica, Lucas eOgura, Simon E Alfred, Linda eBrzustowicz, Anne eBassett
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Neurology
Subjects:
22q11 Deletion Syndrome
DiGeorge Syndrome
Dopamine
Gene Dosage
Schizophrenia
Glutamate
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00238/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00238/full

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