The metabolic adaptation of bile acids and cholesterol after biliary atresia in lamprey via transcriptome-based analysis

The metabolic adaptation of bile acids and cholesterol after biliary atresia in lamprey via transcriptome-based analysis

Lamprey underwent biliary atresia (BA) at its metamorphosis stage. In contrast to patients with BA who develop progressive disease, lamprey can grow and develop normally, suggesting that lamprey has several adaptations for BA. Here we show that adaptive changes in bile acid and cholesterol metabolis...

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Bibliographic Details
Main Authors: Qipeng Zhang, Jilong Pan, Yingying Zhu, Jindi Liu, Yue Pang, Jiarui Li, Pengju Han, Meng Gou, Jun Li, Peng Su, Qingwei Li, Yan Chi
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
Lamprey
Biliary atresia
Metabolic adaptation
Bile acids and cholesterol metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023063156

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http://www.sciencedirect.com/science/article/pii/S2405844023063156

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